Hypoxia does not predict lack of benefit from adjuvant radiotherapy for patients with early stage breast cancer.

ABSTRACT

There is a need to identify patients with early stage breast cancer for whom radiotherapy and its associated toxicities might be avoided. Tutzauer et al. hypothesised that a hypoxia biomarker might be used but found that adjuvant radiotherapy following surgery reduces risk of recurrence irrespective of hypoxia status.