Health and cognition among adults with and without Traumatic Brain Injury: A matched case-control study.
Brain Inj
; 36(3): 415-423, 2022 02 23.
Article
em En
| MEDLINE
| ID: mdl-35143349
ABSTRACT
OBJECTIVES:
To evaluate associations between traumatic brain injury (TBI) and presence of health conditions, and to compare associations of health and cognition between TBI cases and controls.METHODS:
This matched case-control study used data from the TBI Model Systems National Database (TBI cases) and Midlife in the United States II and Refresher studies (controls). 248 TBI cases were age-, sex-, race-, and education-matched without replacement to three controls. Cases and controls were compared on prevalence of 18 self-reported conditions, self-rated health, composite scores from the Brief Test of Adult Cognition by Telephone.RESULTS:
The following conditions were significantly more prevalent among TBI cases versus controls anxiety/depression (OR = 3.12, 95% CI 2.20, 4.43, p < .001), chronic sleeping problems (OR = 2.76, 95% CI 1.86, 4.10, p < .001), headache/migraine (OR = 2.61, 95% CI 1.50, 4.54, p = .0007), and stroke (OR = 6.42, 95% CI 2.93, 14.10, p < .001). The relationship between self-rated health and cognition significantly varied by TBI (pinteraction = 0.002).CONCLUSION:
Individuals with TBI have greater odds of selected neurobehavioral conditions compared to their demographically similar uninjured peers. Among persons with TBI there was a stronger association between poorer self-rated health and cognition than controls. TBI is increasingly conceptualized as a chronic disease; current findings suggest post-TBI health management requires cognitive supports.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Transtornos Cognitivos
/
Lesões Encefálicas Traumáticas
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Humans
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article