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Cryptogenic stroke and TIA: Suggested diagnostic approach while waiting for evaluation and treatment guidelines.
Ratajczak-Tretel, Barbara; Lambert, Anna Tancin; Atar, Dan; Aamodt, Anne Hege.
Afiliação
  • Ratajczak-Tretel B; Department of Neurology, Østfold Hospital Trust, Grålum, Norway.
  • Lambert AT; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Atar D; Department of Neurology, Østfold Hospital Trust, Grålum, Norway.
  • Aamodt AH; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Acta Neurol Scand ; 145(5): 641-646, 2022 May.
Article em En | MEDLINE | ID: mdl-35146751
BACKGROUND: Empiric strategies for secondary prevention in cryptogenic stroke and cryptogenic TIA are lacking. The best therapy to prevent recurrence depends on the cause of stroke. Attempting a correct diagnosis is therefore the fundamental goal of stroke treatment. Further investigation into the source of embolism if suspected, and determination of the etiology, even if demanding, is the needed prerequisite for optimal secondary prevention and risk reduction. AIMS: This paper discusses evaluation and treatment of cryptogenic stroke in light of recent years' clinical trials results and developments in cardiology and neuroradiology. No ethical approval was needed for this work. RESULTS: Cardioembolism due to paroxysmal atrial fibrillation, patent foramen ovale, or cardiomyopathy; occult atherosclerosis from unstable plaques and hypercoagulable conditions seem to be the most common underlying causes to be revealed by further investigations. Treatment of these conditions can reduce the stroke recurrence significantly. CONCLUSIONS: An individual approach and targeted diagnostics using advanced medical technologies in selected patients, who may benefit from a tailored treatment regimen, can help reveal a probable cause in the majority of strokes and TIAs previously classified as cryptogenic.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ataque Isquêmico Transitório / Acidente Vascular Cerebral / Forame Oval Patente / AVC Isquêmico Tipo de estudo: Diagnostic_studies / Guideline Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ataque Isquêmico Transitório / Acidente Vascular Cerebral / Forame Oval Patente / AVC Isquêmico Tipo de estudo: Diagnostic_studies / Guideline Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article