Methyltransferase SETD2 inhibits tumor growth and metastasis via STAT1-IL-8 signaling-mediated epithelial-mesenchymal transition in lung adenocarcinoma.

Yang, Xin; Chen, Rui; Chen, Yan; Zhou, You; Wu, Chen; Li, Qing; Wu, Jun; Hu, Wen-Wei; Zhao, Wei-Qing; Wei, Wei; Shi, Jun-Tao; Ji, Mei

Yang, Xin; Chen, Rui; Chen, Yan; Zhou, You; Wu, Chen; Li, Qing; Wu, Jun; Hu, Wen-Wei; Zhao, Wei-Qing; Wei, Wei; Shi, Jun-Tao; Ji, Mei.

Afiliação

Yang X; Department of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Chen R; Jiangsu Engineering Research Center for Tumor Immunotherapy, Changzhou, China.
Chen Y; Institute of Cell Therapy, Soochow University, Changzhou, China.
Zhou Y; Department of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Wu C; Department of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Li Q; Jiangsu Engineering Research Center for Tumor Immunotherapy, Changzhou, China.
Wu J; Institute of Cell Therapy, Soochow University, Changzhou, China.
Hu WW; Department of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Zhao WQ; Department of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Wei W; Department of Pathology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Shi JT; Department of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Ji M; Department of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, China.

Cancer Sci ; 113(4): 1195-1207, 2022 Apr.

Article em En | MEDLINE | ID: mdl-35152527

Assuntos

Adenocarcinoma de Pulmão; Carcinoma Pulmonar de Células não Pequenas; Neoplasias Pulmonares; Adenocarcinoma de Pulmão/patologia; Movimento Celular/genética; Proliferação de Células/genética; Transição Epitelial-Mesenquimal/genética; Regulação Neoplásica da Expressão Gênica; Histona-Lisina N-Metiltransferase; Humanos; Interleucina-8/genética; Interleucina-8/metabolismo; Neoplasias Pulmonares/patologia; Fator de Transcrição STAT1/genética; Fator de Transcrição STAT1/metabolismo; Transdução de Sinais/genética

Palavras-chave

EMT; IL-8; SETD2; Stat1; lung adenocarcinoma

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Adenocarcinoma de Pulmão / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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