Clinical and Nonclinical Disposition and In Vitro Drug-Drug Interaction Potential of Felcisetrag, a Highly Selective and Potent 5-HT<sub>4</sub> Receptor Agonist.

Pusalkar, Sandeepraj; Chowdhury, Swapan K; Czerniak, Richard; Zhu, Xiaochun; Li, Yuexian; Balani, Suresh K; Ramsden, Diane

Clinical and Nonclinical Disposition and In Vitro Drug-Drug Interaction Potential of Felcisetrag, a Highly Selective and Potent 5-HT₄ Receptor Agonist.

Pusalkar, Sandeepraj; Chowdhury, Swapan K; Czerniak, Richard; Zhu, Xiaochun; Li, Yuexian; Balani, Suresh K; Ramsden, Diane.

Afiliação

Pusalkar S; Global; Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc., 35 Landsdowne Street, Cambridge, MA, 02139, USA.
Chowdhury SK; Servier Pharmaceuticals, Cambridge, MA, USA.
Czerniak R; Global; Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc., 35 Landsdowne Street, Cambridge, MA, 02139, USA.
Zhu X; Boston Pharmaceuticals, Cambridge, MA, USA.
Li Y; Global; Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc., 35 Landsdowne Street, Cambridge, MA, 02139, USA.
Balani SK; Global; Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc., 35 Landsdowne Street, Cambridge, MA, 02139, USA.
Ramsden D; Global; Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc., 35 Landsdowne Street, Cambridge, MA, 02139, USA.

Eur J Drug Metab Pharmacokinet ; 47(3): 371-386, 2022 May.

Article em En | MEDLINE | ID: mdl-35157234

Assuntos

Sistema Enzimático do Citocromo P-450; Serotonina; Animais; Cães; Interações Medicamentosas; Humanos; Ratos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Serotonina / Sistema Enzimático do Citocromo P-450 Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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