Tadalafil Treatment of Mice with Fetal Growth Restriction and Preeclampsia Improves Placental mTOR Signaling.

Tanaka, Kayo; Tanaka, Hiroaki; Tachibana, Ryota; Yoshikawa, Kento; Kawamura, Takuya; Takakura, Sho; Takeuchi, Hiroki; Ikeda, Tomoaki

Tanaka, Kayo; Tanaka, Hiroaki; Tachibana, Ryota; Yoshikawa, Kento; Kawamura, Takuya; Takakura, Sho; Takeuchi, Hiroki; Ikeda, Tomoaki.

Afiliação

Tanaka K; Department of Obstetrics and Gynecology, Mie University School of Medicine, Edobashi, Tsu 5148507, Mie, Japan.
Tanaka H; Department of Obstetrics and Gynecology, Mie University School of Medicine, Edobashi, Tsu 5148507, Mie, Japan.
Tachibana R; Department of Obstetrics and Gynecology, Mie University School of Medicine, Edobashi, Tsu 5148507, Mie, Japan.
Yoshikawa K; Department of Obstetrics and Gynecology, Mie University School of Medicine, Edobashi, Tsu 5148507, Mie, Japan.
Kawamura T; Department of Obstetrics and Gynecology, Mie University School of Medicine, Edobashi, Tsu 5148507, Mie, Japan.
Takakura S; Department of Obstetrics and Gynecology, Mie University School of Medicine, Edobashi, Tsu 5148507, Mie, Japan.
Takeuchi H; Department of Obstetrics and Gynecology, Mie University School of Medicine, Edobashi, Tsu 5148507, Mie, Japan.
Ikeda T; Department of Obstetrics and Gynecology, Mie University School of Medicine, Edobashi, Tsu 5148507, Mie, Japan.

Int J Mol Sci ; 23(3)2022 Jan 27.

Article em En | MEDLINE | ID: mdl-35163395

Assuntos

Retardo do Crescimento Fetal; Pré-Eclâmpsia; Transdução de Sinais/efeitos dos fármacos; Serina-Treonina Quinases TOR/metabolismo; Tadalafila/farmacologia; Animais; Feminino; Retardo do Crescimento Fetal/induzido quimicamente; Retardo do Crescimento Fetal/tratamento farmacológico; Retardo do Crescimento Fetal/metabolismo; Camundongos; NG-Nitroarginina Metil Éster/efeitos adversos; NG-Nitroarginina Metil Éster/farmacologia; Placenta; Pré-Eclâmpsia/induzido quimicamente; Pré-Eclâmpsia/tratamento farmacológico; Pré-Eclâmpsia/metabolismo; Gravidez

Palavras-chave

L-NAME; fetal growth restriction; mTOR signaling; placenta; preeclampsia; tadalafil

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pré-Eclâmpsia / Transdução de Sinais / Serina-Treonina Quinases TOR / Retardo do Crescimento Fetal / Tadalafila Limite: Animals / Pregnancy Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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