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Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes.
Zheng, Xiaowei; Narayanan, Sampath; Xu, Cheng; Eliasson Angelstig, Sofie; Grünler, Jacob; Zhao, Allan; Di Toro, Alessandro; Bernardi, Luciano; Mazzone, Massimiliano; Carmeliet, Peter; Del Sole, Marianna; Solaini, Giancarlo; Forsberg, Elisabete A; Zhang, Ao; Brismar, Kerstin; Schiffer, Tomas A; Rajamand Ekberg, Neda; Botusan, Ileana Ruxandra; Palm, Fredrik; Catrina, Sergiu-Bogdan.
Afiliação
  • Zheng X; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Narayanan S; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Xu C; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Eliasson Angelstig S; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Grünler J; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Zhao A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Di Toro A; Centre for Inherited Cardiovascular Diseases, IRCCS Foundation University Hospital Policlinico San Matteo, Pavia, Italy.
  • Bernardi L; Folkälsan Research Center, Folkälsan Institute of Genetics, University of Helsinki, Helsinki, Finland.
  • Mazzone M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Vlaams Instituut voor Biotechnologie (VIB); Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, Katholieke Universiteit (KU) Leuven, Leuven, Belgium.
  • Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, Katholieke Universiteit (KU) Leuven; Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Center, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium.
  • Del Sole M; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Solaini G; Dipartimento di Biochimica, Università di Bologna, Bologna, Italy.
  • Forsberg EA; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Zhang A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Brismar K; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Schiffer TA; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
  • Rajamand Ekberg N; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Botusan IR; Department of Endocrinology and Diabetes, Karolinska University Hospital, Stockholm, Sweden.
  • Palm F; Center for Diabetes, Academic Specialist Centrum, Stockholm, Sweden.
  • Catrina SB; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Elife ; 112022 02 15.
Article em En | MEDLINE | ID: mdl-35164902

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espécies Reativas de Oxigênio / Diabetes Mellitus / Fator 1 Induzível por Hipóxia / Hipóxia / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espécies Reativas de Oxigênio / Diabetes Mellitus / Fator 1 Induzível por Hipóxia / Hipóxia / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article