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Inhibition of HIF-1α-AQP4 axis ameliorates brain edema and neurological functional deficits in a rat controlled cortical injury (CCI) model.
Xiong, Ao; Li, Junxia; Xiong, Renping; Xia, Yiming; Jiang, Xu; Cao, Fuyang; Lu, Hong; Xu, Jianzhong; Shan, Fabo.
Afiliação
  • Xiong A; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Army Occupational Disease, Research Institute of Surgery, Daping Hospital, Army Medical University, Chongqing, 400042, China.
  • Li J; Department of Orthopaedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450042, Henan, China.
  • Xiong R; State Key Laboratory of Trauma, Burns and Combined Injury, Research Department of Traumatic Shock and Blood Transfusion, Research Institute of Surgery, Daping Hospital, Army Medical University, Chongqing, 400042, China.
  • Xia Y; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Army Occupational Disease, Research Institute of Surgery, Daping Hospital, Army Medical University, Chongqing, 400042, China.
  • Jiang X; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Army Occupational Disease, Research Institute of Surgery, Daping Hospital, Army Medical University, Chongqing, 400042, China.
  • Cao F; Department of Orthopaedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450042, Henan, China.
  • Lu H; Department of Orthopaedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450042, Henan, China.
  • Xu J; Department of Radiology, Chongqing No. 7 Hospital of Chongqing University of Technology, Chongqing, 400054, China.
  • Shan F; Department of Orthopaedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450042, Henan, China. 13937133786@163.com.
Sci Rep ; 12(1): 2701, 2022 02 17.
Article em En | MEDLINE | ID: mdl-35177771
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Edema Encefálico / Córtex Cerebral / Aquaporina 4 / Subunidade alfa do Fator 1 Induzível por Hipóxia / Neurônios Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Edema Encefálico / Córtex Cerebral / Aquaporina 4 / Subunidade alfa do Fator 1 Induzível por Hipóxia / Neurônios Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article