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Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity.
Uzzan, Mathieu; Martin, Jerome C; Mesin, Luka; Livanos, Alexandra E; Castro-Dopico, Tomas; Huang, Ruiqi; Petralia, Francesca; Magri, Giuliana; Kumar, Shashi; Zhao, Qing; Rosenstein, Adam K; Tokuyama, Minami; Sharma, Keshav; Ungaro, Ryan; Kosoy, Roman; Jha, Divya; Fischer, Jeremy; Singh, Harpriya; Keir, Mary E; Ramamoorthi, Nandhini; O'Gorman, William E; Cohen, Benjamin L; Rahman, Adeeb; Cossarini, Francesca; Seki, Akihiro; Leyre, Louise; Vaquero, Sonia Tejedor; Gurunathan, Sakteesh; Grasset, Emilie K; Losic, Bojan; Dubinsky, Marla; Greenstein, Alexander J; Gottlieb, Zoe; Legnani, Peter; George, James; Irizar, Haritz; Stojmirovic, Aleksandar; Brodmerkel, Carrie; Kasarkis, Andrew; Sands, Bruce E; Furtado, Glaucia; Lira, Sergio A; Tuong, Zewen K; Ko, Huaibin M; Cerutti, Andrea; Elson, Charles O; Clatworthy, Menna R; Merad, Miriam; Suárez-Fariñas, Mayte; Argmann, Carmen.
Afiliação
  • Uzzan M; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Martin JC; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Mesin L; Paris Est Créteil University UPEC, Assistance Publique-Hôpitaux de Paris (AP-HP), Henri Mondor Hospital, Fédération Hospitalo-Universitaire, InnovaTive theRapy for immUne disordErs (TRUE), Gastroenterology Department, Créteil, France.
  • Livanos AE; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Castro-Dopico T; Université de Nantes, INSERM, CHU Nantes, Centre de Recherche en Transplantation et Immunologie, Nantes, France.
  • Huang R; CHU Nantes, Laboratoire d'Immunologie, Center for Immuno Monitoring Nantes-Atlantique (CIMNA), Nantes, France.
  • Petralia F; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.
  • Magri G; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Kumar S; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Zhao Q; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Rosenstein AK; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Tokuyama M; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge, UK.
  • Sharma K; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Ungaro R; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Kosoy R; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Jha D; Translational Clinical Research Program, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.
  • Fischer J; Washington University School of Medicine, St. Louis, MO, USA.
  • Singh H; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Keir ME; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Ramamoorthi N; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • O'Gorman WE; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Cohen BL; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Rahman A; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Cossarini F; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Seki A; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Leyre L; Icahn Institute for Data Science and Genomic Technology, New York, NY, USA.
  • Vaquero ST; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Gurunathan S; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Grasset EK; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Losic B; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Dubinsky M; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Greenstein AJ; Biomarker Discovery, OMNI, Genentech Inc., South San Francisco, CA, USA.
  • Gottlieb Z; Biomarker Discovery, OMNI, Genentech Inc., South San Francisco, CA, USA.
  • Legnani P; OMNI Biomarker Development, Genentech Inc., South San Francisco, CA, USA.
  • George J; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Irizar H; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Stojmirovic A; Human Immune Monitoring Core, Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Brodmerkel C; Immunai, New York NY, USA.
  • Kasarkis A; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Sands BE; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Furtado G; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Lira SA; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Tuong ZK; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Ko HM; Translational Clinical Research Program, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.
  • Cerutti A; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Elson CO; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Clatworthy MR; Department of Medicine Division of Clinical Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Merad M; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Suárez-Fariñas M; Icahn Institute for Data Science and Genomic Technology, New York, NY, USA.
  • Argmann C; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Nat Med ; 28(4): 766-779, 2022 04.
Article em En | MEDLINE | ID: mdl-35190725
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmócitos / Colite Ulcerativa Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmócitos / Colite Ulcerativa Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article