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Design, synthesis and biological evaluation of colchicine glycoconjugates as tubulin polymerization inhibitors.
Wang, Zhan; Liu, Runlai; Zhang, Xin; Chang, Xing; Gao, Minghuan; Zhang, Shuai; Guan, Qi; Sun, Jun; Zuo, Daiying; Zhang, Weige.
Afiliação
  • Wang Z; Pharmaceutical Department, The First Affiliated Hospital of Zhengzhou University, 1 Jianshedong Road, Erqi District, Zhengzhou 450052, China.
  • Liu R; Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Zhang X; Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Chang X; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Gao M; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Zhang S; Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Guan Q; Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China. Electronic address: guanqi@syphu.edu.cn.
  • Sun J; Clinical Pharmacology Laboratory, Henan Province People's Hospital, Zhengzhou University People's Hospital, 7 Weiwu Road, Jinshui District, Zhengzhou 450003, China. Electronic address: Jun_84@163.com.
  • Zuo D; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China. Electronic address: zuodaiying@163.com.
  • Zhang W; Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China. Electronic address: zhangweige2000@sina.com.
Bioorg Med Chem ; 58: 116671, 2022 03 15.
Article em En | MEDLINE | ID: mdl-35193066
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Glicoconjugados / Desenho de Fármacos / Colchicina / Moduladores de Tubulina / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Glicoconjugados / Desenho de Fármacos / Colchicina / Moduladores de Tubulina / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article