In-Hospital and Long-Term Outcomes in Patients with Head and Neck Cancer Bleeding.
Medicina (Kaunas)
; 58(2)2022 Jan 25.
Article
em En
| MEDLINE
| ID: mdl-35208501
ABSTRACT
Background and Objectives:
The purpose of the present study was to elucidate the in-hospital and long-term outcomes of patients with head and neck cancer (HNC) bleeding and to analyze the risk factors for mortality. Materials andMethods:
We included patients who presented to the emergency department (ED) with HNC bleeding. Variables of patients who survived and died were compared and associated factors were investigated by logistic regression and Cox's proportional hazard model.Results:
A total of 125 patients were enrolled in the present study. Fifty-nine (52.8%) patients experienced a recurrent bleeding event. The in-hospital mortality rate was 16%. The overall survival at 1, 3 and 5 years was 48%, 41% and 34%, respectively. The median survival time was 9.2 months. Multivariate logistic regression analyses revealed that risk factors for in-hospital mortality were inotropic support (OR = 10.41; Cl 1.81-59.84; p = 0.009), hypopharyngeal cancer (OR = 4.32; Cl 1.29-14.46; p = 0.018), and M stage (OR = 5.90; Cl 1.07-32.70; p = 0.042). Multivariate Cox regression analyses indicate that heart rate >110 (beats/min) (HR = 2.02; Cl 1.16-3.51; p = 0.013), inotropic support (HR = 3.25; Cl 1.20-8.82; p = 0.021), and hypopharygneal cancer (HR = 2.22; Cl 1.21-4.06; p = 0.010) were all significant independent predictors of poorer overall survival.Conclusions:
HNC bleeding commonly represents the advanced disease stage. Recognition of associated factors aids in the risk stratification of patients with HNC bleeding.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias de Cabeça e Pescoço
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article