Does Exercise Affect Telomere Length? A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Medicina (Kaunas)
; 58(2)2022 Feb 05.
Article
em En
| MEDLINE
| ID: mdl-35208566
ABSTRACT
Background and objectives:
Telomere length is an indicator of biological aging, and it shortens during cell division. A short telomere length is associated with various age-related diseases and mortality. It is suggested that physical activity has a positive effect on the rate of telomere length shortening. Materials andMethods:
Related studies, published in electronic databases, were searched with keywords, including exercise, telomere length, and randomized controlled trial. The data were weighted and pooled through a fixed-effect model.Results:
Of the total 49 studies searched, 7 studies with 939 participants were considered suitable, and were analyzed qualitatively and quantitatively. Exercise is beneficial to telomere length. Aerobic exercise was effective as the type of exercise (MD, -0.03; 95% CI, -0.04 to -0.01). In addition, exercise for more than 6 months, with a change in lifestyle, is beneficial for telomere length (MD, -0.02; 95% CI, -0.04 to -0.01).Conclusions:
The type and duration of exercise for positive improvement in telomere length is aerobic exercise for more than 6 months.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Exercício Físico
/
Estilo de Vida
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
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Systematic_reviews
Limite:
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article