Exploring statistical weight estimates for mitochondrial DNA matches involving heteroplasmy.

McElhoe, Jennifer A; Wilton, Peter R; Parson, Walther; Holland, Mitchell M

McElhoe, Jennifer A; Wilton, Peter R; Parson, Walther; Holland, Mitchell M.

Afiliação

McElhoe JA; Department of Biochemistry & Molecular Biology, Forensic Science Program, The Pennsylvania State University, University Park, 014 Thomas Building, State College, PA, 16802, USA. jam760@psu.edu.
Wilton PR; Department of Integrative Biology, University of California, Berkeley, CA, 94720, USA.
Parson W; 23andMe Inc, Sunnyvale, CA, 94086, USA.
Holland MM; Department of Biochemistry & Molecular Biology, Forensic Science Program, The Pennsylvania State University, University Park, 014 Thomas Building, State College, PA, 16802, USA.

Int J Legal Med ; 136(3): 671-685, 2022 May.

Article em En | MEDLINE | ID: mdl-35243529

Assuntos

DNA Mitocondrial; Genoma Mitocondrial; DNA Mitocondrial/genética; Heteroplasmia; Sequenciamento de Nucleotídeos em Larga Escala/métodos; Humanos; Filogenia; Análise de Sequência de DNA

Palavras-chave

Control region; Forensic mtDNA; Forensic statistics; Massively parallel sequencing; MiSeq; Rates of mtDNA heteroplasmy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Genoma Mitocondrial Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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