Quo vadis, neutrophil?

Gonzalez, Rodrigo J; von Andrian, Ulrich H

Gonzalez, Rodrigo J; von Andrian, Ulrich H.

Afiliação

Gonzalez RJ; Department of Immunology, Harvard Medical School, Boston, MA, USA; The Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
von Andrian UH; Department of Immunology, Harvard Medical School, Boston, MA, USA; The Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA. Electronic address: uva@hms.harvard.edu.

Cell ; 185(5): 759-761, 2022 03 03.

Article em En | MEDLINE | ID: mdl-35245478

ABSTRACT

ABSTRACT

Neutrophil recruitment from blood into tissues is a hallmark of inflammation and anti-microbial host defense. In this issue, De Giovanni et al. describe an unanticipated role for a serotonin metabolite, 5-HIAA, which is produced by activated platelets and mast cells and engages the orphan receptor, GPR35, to recruit neutrophils to inflamed tissues.

Assuntos

Plaquetas; Neutrófilos; Plaquetas/metabolismo; Humanos; Inflamação/metabolismo; Mastócitos/metabolismo; Infiltração de Neutrófilos; Neutrófilos/metabolismo

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plaquetas / Neutrófilos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plaquetas / Neutrófilos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article