Endothelial cyclin I reduces vulnerability to angiotensin II-induced vascular remodeling and abdominal aortic aneurysm risk.

Zhao, Wei; Yao, Mengyu; Zhang, Yunyi; Xiong, Da; Dai, Guolin; Zhang, Jinpin; Cao, Yu; Li, Hongrong

Zhao, Wei; Yao, Mengyu; Zhang, Yunyi; Xiong, Da; Dai, Guolin; Zhang, Jinpin; Cao, Yu; Li, Hongrong.

Afiliação

Zhao W; Department of Cardiovascular Surgery, The First People's Hospital of Yunnan Province, China; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
Yao M; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
Zhang Y; Department of Cardiovascular Surgery, The First People's Hospital of Yunnan Province, China; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
Xiong D; Department of Cardiovascular Surgery, The First People's Hospital of Yunnan Province, China; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
Dai G; Department of Cardiovascular Surgery, The First People's Hospital of Yunnan Province, China; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
Zhang J; Department of Hematopathology, The First People's Hospital of Yunnan Province, China.
Cao Y; Department of Cardiovascular Surgery, The First People's Hospital of Yunnan Province, China; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China. Electronic address: 18687035472@163.com.
Li H; Department of Cardiovascular Surgery, The First People's Hospital of Yunnan Province, China; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China. Electronic address: hongrongli_khyy@163.com.

Microvasc Res ; 142: 104348, 2022 07.

Article em En | MEDLINE | ID: mdl-35245516

Assuntos

Angiotensina II; Aneurisma da Aorta Abdominal; Hipertensão; Remodelação Vascular; Angiotensina II/farmacologia; Animais; Aneurisma da Aorta Abdominal/induzido quimicamente; Aneurisma da Aorta Abdominal/genética; Aneurisma da Aorta Abdominal/prevenção & controle; Biopterinas/metabolismo; Cloreto de Cálcio/metabolismo; Ciclina I/metabolismo; Proteína Rica em Cisteína 61/metabolismo; Modelos Animais de Doenças; Células Endoteliais/metabolismo; Endotélio/metabolismo; Humanos; Peróxido de Hidrogênio/metabolismo; Hipertensão/genética; Hipertensão/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; RNA Mensageiro/metabolismo; Tetra-Hidrofolato Desidrogenase/genética; Tetra-Hidrofolato Desidrogenase/metabolismo

Palavras-chave

AAA; Ang II; Aortic aneurysm; BH4; Ccni; Dhfr; Rb

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Angiotensina II / Aneurisma da Aorta Abdominal / Remodelação Vascular / Hipertensão Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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