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Inhibitors of ERp44, PDIA1, and AGR2 induce disulfide-mediated oligomerization of Death Receptors 4 and 5 and cancer cell death.
Law, Mary E; Yaaghubi, Elham; Ghilardi, Amanda F; Davis, Bradley J; Ferreira, Renan B; Koh, Jin; Chen, Sixue; DePeter, Sadie F; Schilson, Christopher M; Chiang, Chi-Wu; Heldermon, Coy D; Nørgaard, Peter; Castellano, Ronald K; Law, Brian K.
Afiliação
  • Law ME; Department of Pharmacology & Therapeutics, University of Florida, Gainesville, FL, 32610, USA.
  • Yaaghubi E; Department of Chemistry, University of Florida, Gainesville, FL, 32611, USA.
  • Ghilardi AF; Department of Chemistry, University of Florida, Gainesville, FL, 32611, USA.
  • Davis BJ; Department of Pharmacology & Therapeutics, University of Florida, Gainesville, FL, 32610, USA.
  • Ferreira RB; Department of Chemistry, University of Florida, Gainesville, FL, 32611, USA.
  • Koh J; Proteomics and Mass Spectrometry Facility, Interdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, FL, 32610, USA.
  • Chen S; Proteomics and Mass Spectrometry Facility, Interdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, FL, 32610, USA; Department of Biology, Genetics Institute, University of Florida, Gainesville, FL, 32610, USA.
  • DePeter SF; Department of Chemistry, University of Florida, Gainesville, FL, 32611, USA.
  • Schilson CM; Department of Chemistry, University of Florida, Gainesville, FL, 32611, USA.
  • Chiang CW; Institute of Molecular Medicine, College of Medicine and Center for Infectious Disease and Signaling Research, National Cheng Kung University, Tainan, Taiwan.
  • Heldermon CD; Department of Medicine, University of Florida, Gainesville, FL, 32610, USA; UF-Health Cancer Center, University of Florida, Gainesville, FL, 32610, USA.
  • Nørgaard P; Department of Pathology, Copenhagen University Hospital Herlev, DK, 2730, Herlev, Denmark.
  • Castellano RK; Department of Chemistry, University of Florida, Gainesville, FL, 32611, USA; UF-Health Cancer Center, University of Florida, Gainesville, FL, 32610, USA. Electronic address: castellano@chem.ufl.edu.
  • Law BK; Department of Pharmacology & Therapeutics, University of Florida, Gainesville, FL, 32610, USA; UF-Health Cancer Center, University of Florida, Gainesville, FL, 32610, USA. Electronic address: bklaw@ufl.edu.
Cancer Lett ; 534: 215604, 2022 05 28.
Article em En | MEDLINE | ID: mdl-35247515
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Dissulfetos Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Dissulfetos Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article