Biosynthesis and cytotoxic effect of silymarin-functionalized selenium nanoparticles induced autophagy mediated cellular apoptosis via downregulation of PI3K/Akt/mTOR pathway in gastric cancer.

Mi, Xiao-Jie; Choi, Han Sol; Perumalsamy, Haribalan; Shanmugam, Rajeshkumar; Thangavelu, Lakshmi; Balusamy, Sri Renukadevi; Kim, Yeon-Ju

Mi, Xiao-Jie; Choi, Han Sol; Perumalsamy, Haribalan; Shanmugam, Rajeshkumar; Thangavelu, Lakshmi; Balusamy, Sri Renukadevi; Kim, Yeon-Ju.

Afiliação

Mi XJ; Graduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, 17104, Gyeonggi-do, Republic of Korea.
Choi HS; Graduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, 17104, Gyeonggi-do, Republic of Korea.
Perumalsamy H; Graduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, 17104, Gyeonggi-do, Republic of Korea; Research Institute for Convergence of Basic Science, Hanyang University, Seoul 04763, Republic of Korea.
Shanmugam R; Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha University, SIMATS, Chennai 600077, TN, India.
Thangavelu L; Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha University, SIMATS, Chennai 600077, TN, India.
Balusamy SR; Department of Food Science and Biotechnology, Sejong University, Gwangjin-gu, Seoul, 05006, Republic of Korea. Electronic address: renubalu@sejong.ac.kr.
Kim YJ; Graduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, 17104, Gyeonggi-do, Republic of Korea. Electronic address: yeonjukim@khu.ac.kr.

Phytomedicine ; 99: 154014, 2022 May.

Article em En | MEDLINE | ID: mdl-35247670