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DL-3-n-butylphthalide prevents oxidative stress and atherosclerosis by targeting Keap-1 and inhibiting Keap-1/Nrf-2 interaction.
Han, Jibo; Shi, Xiaowen; Xu, Jiajun; Lin, Wante; Chen, Yanghao; Han, Bingjiang; Wang, Yi; Xu, Jianjiang.
Afiliação
  • Han J; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China, 325000; Department of Cardiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China, 314000.
  • Shi X; Department of Cardiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China, 314000.
  • Xu J; Department of Cardiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China, 314000.
  • Lin W; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China, 325000.
  • Chen Y; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China, 325000.
  • Han B; Department of Cardiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China, 314000.
  • Wang Y; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China, 325000. Electronic address: yi.wang1122@wmu.edu.cn.
  • Xu J; Department of Cardiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China, 314000. Electronic address: jjxvjx2y@163.com.
Eur J Pharm Sci ; 172: 106164, 2022 May 01.
Article em En | MEDLINE | ID: mdl-35259495
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Isquemia Encefálica / Fármacos Neuroprotetores / Acidente Vascular Cerebral / Aterosclerose Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Isquemia Encefálica / Fármacos Neuroprotetores / Acidente Vascular Cerebral / Aterosclerose Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article