In Silico Designed Gain-of-Function Variants of Complement C2 Support Cytocidal Activity of Anticancer Monoclonal Antibodies.

Urban, Aleksandra; Majeranowski, Alan; Stasilojc, Grzegorz; Koszalka, Patrycja; Felberg, Anna; Taszner, Michal; Zaucha, Jan M; Okrój, Marcin.

Afiliação

Urban A; Department of Cell Biology and Immunology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Debinki 1 Street, 80-211 Gdansk, Poland.
Majeranowski A; Department of Cell Biology and Immunology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Debinki 1 Street, 80-211 Gdansk, Poland.
Stasilojc G; Department of Hematology and Transplantology, Medical University of Gdansk, Smoluchowskiego 17 Street, 80-214 Gdansk, Poland.
Koszalka P; Department of Cell Biology and Immunology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Debinki 1 Street, 80-211 Gdansk, Poland.
Felberg A; Department of Cell Biology and Immunology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Debinki 1 Street, 80-211 Gdansk, Poland.
Taszner M; Department of Cell Biology and Immunology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Debinki 1 Street, 80-211 Gdansk, Poland.
Zaucha JM; Department of Hematology and Transplantology, Medical University of Gdansk, Smoluchowskiego 17 Street, 80-214 Gdansk, Poland.
Okrój M; Department of Hematology and Transplantology, Medical University of Gdansk, Smoluchowskiego 17 Street, 80-214 Gdansk, Poland.

Cancers (Basel) ; 14(5)2022 Mar 01.

Article em En | MEDLINE | ID: mdl-35267578