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Discovery of tricyclic HIV-1 integrase-LEDGF/p75 allosteric inhibitors by intramolecular direct arylation reaction.
Taoda, Yoshiyuki; Akiyama, Toshiyuki; Tomita, Kenji; Fujiwara-Kitamura, Misato; Tamura, Yoshinori; Kawasuji, Takashi; Matsuoka, Eriko; Akihisa, Erika; Seki, Takahiro; Yoshinaga, Tomokazu.
Afiliação
  • Taoda Y; Shionogi Pharmaceutical Research Center, Shionogi & Company, Limited, 1-1, Futabacho, 3-chome, Toyonaka 561-0825, Japan. Electronic address: yoshiyuki.taoda@shionogi.co.jp.
  • Akiyama T; Shionogi Pharmaceutical Research Center, Shionogi & Company, Limited, 1-1, Futabacho, 3-chome, Toyonaka 561-0825, Japan.
  • Tomita K; Shionogi Pharmaceutical Research Center, Shionogi & Company, Limited, 1-1, Futabacho, 3-chome, Toyonaka 561-0825, Japan.
  • Fujiwara-Kitamura M; Shionogi Pharmaceutical Research Center, Shionogi & Company, Limited, 1-1, Futabacho, 3-chome, Toyonaka 561-0825, Japan.
  • Tamura Y; Shionogi Pharmaceutical Research Center, Shionogi & Company, Limited, 1-1, Futabacho, 3-chome, Toyonaka 561-0825, Japan.
  • Kawasuji T; Shionogi Pharmaceutical Research Center, Shionogi & Company, Limited, 1-1, Futabacho, 3-chome, Toyonaka 561-0825, Japan.
  • Matsuoka E; Shionogi Pharmaceutical Research Center, Shionogi & Company, Limited, 1-1, Futabacho, 3-chome, Toyonaka 561-0825, Japan.
  • Akihisa E; Shionogi Pharmaceutical Research Center, Shionogi & Company, Limited, 1-1, Futabacho, 3-chome, Toyonaka 561-0825, Japan.
  • Seki T; Shionogi Pharmaceutical Research Center, Shionogi & Company, Limited, 1-1, Futabacho, 3-chome, Toyonaka 561-0825, Japan.
  • Yoshinaga T; Shionogi Pharmaceutical Research Center, Shionogi & Company, Limited, 1-1, Futabacho, 3-chome, Toyonaka 561-0825, Japan.
Bioorg Med Chem Lett ; 64: 128664, 2022 05 15.
Article em En | MEDLINE | ID: mdl-35272008
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Integrase de HIV / Integrase de HIV Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Integrase de HIV / Integrase de HIV Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article