Chiral rhodium(III)-azobenzene complexes as photoswitchable DNA molecular locks.
Chem Commun (Camb)
; 58(27): 4324-4327, 2022 Mar 31.
Article
em En
| MEDLINE
| ID: mdl-35274116
ABSTRACT
Chiral rhodium(III)-azobenzene complexes that are able to intercalate into DNA were developed. Upon light exposure, the azobenzene moiety of the metal complexes can photoisomerize from the trans-form to the cis-form, and strongly stabilize the DNA double-helix and modulate DNA transcription. This study presents the first example of metal-based photoswitchable DNA molecular locks.
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MEDLINE
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En
Ano de publicação:
2022
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Article