Erythrocyte Sedimentation: Collapse of a High-Volume-Fraction Soft-Particle Gel.
Phys Rev Lett
; 128(8): 088101, 2022 Feb 25.
Article
em En
| MEDLINE
| ID: mdl-35275655
ABSTRACT
The erythrocyte sedimentation rate is one of the oldest medical diagnostic methods whose physical mechanisms remain debatable today. Using both light microscopy and mesoscale cell-level simulations, we show that erythrocytes form a soft-particle gel. Furthermore, the high volume fraction of erythrocytes, their deformability, and weak attraction lead to unusual properties of this gel. A theoretical model for the gravitational collapse is developed, whose predictions are in agreement with detailed macroscopic measurements of the interface velocity.
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1
Base de dados:
MEDLINE
Assunto principal:
Eritrócitos
/
Modelos Teóricos
Tipo de estudo:
Prognostic_studies
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article