Periplaneta americana extract ameliorates dextran sulfate sodium-induced ulcerative colitis via immunoregulatory and PI3K/AKT/NF-&#954;B signaling pathways.

Ni, Lianli; Lu, Qian; Tang, Miao; Tao, Lu; Zhao, Hairong; Zhang, Chenggui; Yu, Yun; Wu, Xiumei; Liu, Heng; Cui, Ri

Periplaneta americana extract ameliorates dextran sulfate sodium-induced ulcerative colitis via immunoregulatory and PI3K/AKT/NF-κB signaling pathways.

Ni, Lianli; Lu, Qian; Tang, Miao; Tao, Lu; Zhao, Hairong; Zhang, Chenggui; Yu, Yun; Wu, Xiumei; Liu, Heng; Cui, Ri.

Afiliação

Ni L; Cancer and Anticancer Drug Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China.
Lu Q; Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, College of Pharmacy, Dali University, Yunnan, 671000, China.
Tang M; Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, College of Pharmacy, Dali University, Yunnan, 671000, China.
Tao L; National-Local Joint Engineering Research Center of Entomoceutics, College of Pharmacy, Dali University, Yunnan, 671000, China.
Zhao H; Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, College of Pharmacy, Dali University, Yunnan, 671000, China.
Zhang C; National-Local Joint Engineering Research Center of Entomoceutics, College of Pharmacy, Dali University, Yunnan, 671000, China.
Yu Y; Cancer and Anticancer Drug Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China.
Wu X; Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, College of Pharmacy, Dali University, Yunnan, 671000, China.
Liu H; National-Local Joint Engineering Research Center of Entomoceutics, College of Pharmacy, Dali University, Yunnan, 671000, China.
Cui R; Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, College of Pharmacy, Dali University, Yunnan, 671000, China.

Inflammopharmacology ; 30(3): 907-918, 2022 Jun.

Article em En | MEDLINE | ID: mdl-35303235

Assuntos

Colite Ulcerativa; Colite; Periplaneta; Animais; Colite/tratamento farmacológico; Colite Ulcerativa/induzido quimicamente; Colite Ulcerativa/tratamento farmacológico; Colite Ulcerativa/patologia; Colo; Sulfato de Dextrana/farmacologia; Modelos Animais de Doenças; Fatores de Transcrição Forkhead/metabolismo; Imunidade; Interleucina-17/metabolismo; Interleucina-4/metabolismo; Camundongos; NF-kappa B/metabolismo; Periplaneta/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Extratos Vegetais/farmacologia; Extratos Vegetais/uso terapêutico; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais

Palavras-chave

Dextran sulfate sodium; Immune regulation; PI3K/AKT/NF-κB signaling pathway; Periplaneta americana; Ulcerative colitis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Periplaneta / Colite Ulcerativa / Colite Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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