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Paip2A inhibits translation by competitively binding to the RNA recognition motifs of PABPC1 and promoting its dissociation from the poly(A) tail.
Sagae, Takeru; Yokogawa, Mariko; Sawazaki, Ryoichi; Ishii, Yuichiro; Hosoda, Nao; Hoshino, Shin-Ichi; Imai, Shunsuke; Shimada, Ichio; Osawa, Masanori.
Afiliação
  • Sagae T; Graduate School of Pharmaceutical Sciences, Keio University, Minato-ku, Tokyo, Japan.
  • Yokogawa M; Graduate School of Pharmaceutical Sciences, Keio University, Minato-ku, Tokyo, Japan.
  • Sawazaki R; Graduate School of Pharmaceutical Sciences, Keio University, Minato-ku, Tokyo, Japan.
  • Ishii Y; Graduate School of Pharmaceutical Sciences, Keio University, Minato-ku, Tokyo, Japan.
  • Hosoda N; Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho-ku, Nagoya, Japan.
  • Hoshino SI; Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho-ku, Nagoya, Japan.
  • Imai S; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan; Center for Biosystems Dynamics Research, RIKEN, Tsurumi-ku, Yokohama, Japan.
  • Shimada I; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan; Center for Biosystems Dynamics Research, RIKEN, Tsurumi-ku, Yokohama, Japan.
  • Osawa M; Graduate School of Pharmaceutical Sciences, Keio University, Minato-ku, Tokyo, Japan. Electronic address: osawa-ms@pha.keio.ac.jp.
J Biol Chem ; 298(5): 101844, 2022 05.
Article em En | MEDLINE | ID: mdl-35307347
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poli A / Biossíntese de Proteínas / Proteínas de Ligação a Poli(A) / Motivo de Reconhecimento de RNA Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poli A / Biossíntese de Proteínas / Proteínas de Ligação a Poli(A) / Motivo de Reconhecimento de RNA Idioma: En Ano de publicação: 2022 Tipo de documento: Article