Potential enhancement of metformin hydrochloride in solidified reverse micellar solution-based PEGylated lipid nanoparticles targeting therapeutic efficacy in diabetes treatment.

Kenechukwu, Franklin Chimaobi; Nnamani, Daniel Okwudili; Duhu, Judith Chekwube; Nmesirionye, Bright Ugochukwu; Momoh, Mumuni Audu; Akpa, Paul Achile; Attama, Anthony Amaechi

Kenechukwu, Franklin Chimaobi; Nnamani, Daniel Okwudili; Duhu, Judith Chekwube; Nmesirionye, Bright Ugochukwu; Momoh, Mumuni Audu; Akpa, Paul Achile; Attama, Anthony Amaechi.

Afiliação

Kenechukwu FC; Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Enugu State, Nigeria.
Nnamani DO; Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Enugu State, Nigeria.
Duhu JC; Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Enugu State, Nigeria.
Nmesirionye BU; Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Enugu State, Nigeria.
Momoh MA; Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Enugu State, Nigeria.
Akpa PA; Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Enugu State, Nigeria.
Attama AA; Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Enugu State, Nigeria.

Heliyon ; 8(3): e09099, 2022 Mar.

Article em En | MEDLINE | ID: mdl-35309393