Label-Free Sensing of Cysteine through Cadmium Ion Coordination: Smartphone-Based Electrochemical Detection.
Chempluschem
; 87(3): e202200040, 2022 Mar 07.
Article
em En
| MEDLINE
| ID: mdl-35319831
ABSTRACT
The detection of biologically important compounds such as cysteine remains a challenge for monitoring body metabolism. This work proposes a transition metal ion coordination-based label-free cysteine sensor with smartphone-based square wave voltammetry sensing system for the point-of-care testing (POCT). In the sensing system, potential excitation and current measurements were accomplished by a miniaturized and integrated circuit board with a smartphone to wirelessly control the system via Bluetooth. The electrochemical currents changed with the cysteine concentrations ranging from 0â
µM to 200â
µM with a linearity correlation coefficient of 0.9915. The limit of detection was as low as 0.0149â
µM for cysteine. The smartphone-based system provides an effective strategy for cysteine detection, and it can also serve as a promising portable sensing platform for the analysis of other small molecules.
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1
Base de dados:
MEDLINE
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article