Cinnamic Acid Improved Lipopolysaccharide-Induced Depressive-Like Behaviors by Inhibiting Neuroinflammation and Oxidative Stress in Mice.

Zhuo, Rengong; Cheng, Xiaoling; Luo, Lili; Yang, Luying; Zhao, Yun; Zhou, Yu; Peng, Lu; Jin, Xin; Cui, Lishan; Liu, Feng; Yang, Lichao

Zhuo, Rengong; Cheng, Xiaoling; Luo, Lili; Yang, Luying; Zhao, Yun; Zhou, Yu; Peng, Lu; Jin, Xin; Cui, Lishan; Liu, Feng; Yang, Lichao.

Afiliação

Zhuo R; Xiamen Key Laboratory of Chiral Drugs, Medical College, Xiamen University, Xiamen, China.
Cheng X; Shenzhen Research Institute of Xiamen University, Shenzhen, China.
Luo L; Xiamen Key Laboratory of Chiral Drugs, Medical College, Xiamen University, Xiamen, China.
Yang L; Xiamen Key Laboratory of Chiral Drugs, Medical College, Xiamen University, Xiamen, China.
Zhao Y; Xiamen Key Laboratory of Chiral Drugs, Medical College, Xiamen University, Xiamen, China.
Zhou Y; Xiamen Key Laboratory of Chiral Drugs, Medical College, Xiamen University, Xiamen, China.
Peng L; Xiamen Key Laboratory of Chiral Drugs, Medical College, Xiamen University, Xiamen, China.
Jin X; Xiamen Key Laboratory of Chiral Drugs, Medical College, Xiamen University, Xiamen, China.
Cui L; Xiamen Key Laboratory of Chiral Drugs, Medical College, Xiamen University, Xiamen, China.
Liu F; Department of Neurology, Xiang'an Branch, The First Affiliated Hospital of Xiamen University, Xiamen University, Xiamen, China.
Yang L; Department of Anesthesiology, Xiang'an Branch, The First Affiliated Hospital of Xiamen University, Xiamen, China.

Pharmacology ; 107(5-6): 281-289, 2022.

Article em En | MEDLINE | ID: mdl-35325888

Assuntos

Transtorno Depressivo Maior; Lipopolissacarídeos; Animais; Fator Neurotrófico Derivado do Encéfalo/metabolismo; Cinamatos; Depressão/induzido quimicamente; Depressão/tratamento farmacológico; Glutationa/metabolismo; Hipocampo/metabolismo; Interleucina-6/metabolismo; Lipopolissacarídeos/toxicidade; Camundongos; Doenças Neuroinflamatórias; Estresse Oxidativo; Superóxido Dismutase; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

Cinnamic acid; Lipopolysaccharide; Major depressive disorder; Neuroinflammation; Oxidative stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lipopolissacarídeos / Transtorno Depressivo Maior Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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