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Anifrolumab efficacy and safety by type I interferon gene signature and clinical subgroups in patients with SLE: post hoc analysis of pooled data from two phase III trials.
Vital, Edward M; Merrill, Joan T; Morand, Eric F; Furie, Richard A; Bruce, Ian N; Tanaka, Yoshiya; Manzi, Susan; Kalunian, Kenneth C; Kalyani, Rubana N; Streicher, Katie; Abreu, Gabriel; Tummala, Raj.
Afiliação
  • Vital EM; Leeds Institute of Rheumatic and Musculoskeletal Medicine, School of Medicine, University of Leeds, Leeds, UK.
  • Merrill JT; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Morand EF; Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.
  • Furie RA; Centre for Inflammatory Disease Monash Health, Monash University, Melbourne, Victoria, Australia.
  • Bruce IN; Division of Rheumatology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Great Neck, New York, USA.
  • Tanaka Y; Centre for Epidemiology Versus Arthritis, The University of Manchester, NIHR Manchester Biomedical Research Centre, Manchester, UK.
  • Manzi S; Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester, UK.
  • Kalunian KC; The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan.
  • Kalyani RN; Lupus Center of Excellence, Autoimmunity Institute, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.
  • Streicher K; Division of Rheumatology, Allergy and Immunology, University of California San Diego, La Jolla, California, USA.
  • Abreu G; BioPharmaceuticals R&D, AstraZeneca US, Gaithersburg, Maryland, USA.
  • Tummala R; BioPharmaceuticals R&D, AstraZeneca US, Gaithersburg, Maryland, USA.
Ann Rheum Dis ; 81(7): 951-961, 2022 07.
Article em En | MEDLINE | ID: mdl-35338035
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Interferon Tipo I / Anticorpos Monoclonais Humanizados / Lúpus Eritematoso Sistêmico Tipo de estudo: Clinical_trials Limite: Female / Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Interferon Tipo I / Anticorpos Monoclonais Humanizados / Lúpus Eritematoso Sistêmico Tipo de estudo: Clinical_trials Limite: Female / Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article