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Prolonged Cotrimoxazole Prophylaxis Has No Impact on Child Growth in the First Two Years of Life: Findings from a Randomized Controlled Trial in Botswana.
Mussa, Aamirah; Powis, Kathleen M; Lockman, Shahin; Ajibola, Gbolahan; Morroni, Chelsea; Smeaton, Laura; Mmalane, Mompati; Makhema, Joseph; Shapiro, Roger L.
Afiliação
  • Mussa A; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana. Electronic address: amussa@bhp.org.bw.
  • Powis KM; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Division of Internal Medicine, Massachusetts General Hospital, Boston, MA; Division of Pediatrics, Massachusetts General Hospital, Boston, MA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health,
  • Lockman S; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA.
  • Ajibola G; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
  • Morroni C; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; MRC Centre for Reproductive Health, University of Edinburgh, Edinburgh, United Kingdom.
  • Smeaton L; Center for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, MA.
  • Mmalane M; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
  • Makhema J; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
  • Shapiro RL; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA.
J Pediatr ; 246: 266-270.e2, 2022 07.
Article em En | MEDLINE | ID: mdl-35351531
We investigated the impact of prolonged cotrimoxazole prophylaxis on growth in 2848 HIV-exposed uninfected children enrolled in the Mpepu study, a randomized, placebo-controlled trial in Botswana. No significant differences in mean weight-for-age, length-for-age, or weight-for-length z scores between placebo and cotrimoxazole arms were observed overall through 18 months.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Combinação Trimetoprima e Sulfametoxazol Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Child / Humans / Infant País como assunto: Africa Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Combinação Trimetoprima e Sulfametoxazol Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Child / Humans / Infant País como assunto: Africa Idioma: En Ano de publicação: 2022 Tipo de documento: Article