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Triplet pregnancy with hydatidiform mole: A report of two cases with literature review.
Sheng, Qing-Jing; Wang, Yu-Mei; Wang, Bei-Ying; Shuai, Wen; He, Xiao-Ying.
Afiliação
  • Sheng QJ; Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
  • Wang YM; Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
  • Wang BY; Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
  • Shuai W; Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
  • He XY; Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
J Obstet Gynaecol Res ; 48(6): 1458-1465, 2022 Jun.
Article em En | MEDLINE | ID: mdl-35352441
ABSTRACT

AIM:

We present two cases of triplet pregnancy with complete hydatidiform mole (CHM) in contrasting outcomes and discuss the complications of mothers and outcomes of fetuses through a literature review, raising an important issue on the management of this special pregnancy.

METHODS:

We share our manage experience for two cases of triplet pregnancy with CHM and retrospectively analyze 18 similar pregnancies reported previously with different pregnancy outcomes.

RESULTS:

In our cases, one case receiving Clomiphene ovulation induction delivered two live fetuses by cesarean section at 30+ weeks without GTN (gestational trophoblastic neoplasia), unfortunately, the other case following ICSI-ET terminated the pregnancy in the setting of complications at 18+ weeks without GTN. No severe complications were detected during pregnancy and no pGTD was developed after delivery in neither of the pregnant.

CONCLUSIONS:

Co-existing complete hydatidiform mole in multiple pregnancies may become more common owing to the spreading use of ART. The decision for whether continue pregnancy depending on the personalized conditions including the complications of the pregnancy, the outcomes of the fetuses, the gestational age for delivery, and the potential progression of persistent gestational trophoblastic disease (pGTD). Furthermore, close monitor is necessary for the pregnant with triplet pregnancy with CHM who want to continue pregnancy.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Uterinas / Mola Hidatiforme / Doença Trofoblástica Gestacional / Gravidez de Trigêmeos Tipo de estudo: Observational_studies / Prognostic_studies / Systematic_reviews Limite: Female / Humans / Pregnancy Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Uterinas / Mola Hidatiforme / Doença Trofoblástica Gestacional / Gravidez de Trigêmeos Tipo de estudo: Observational_studies / Prognostic_studies / Systematic_reviews Limite: Female / Humans / Pregnancy Idioma: En Ano de publicação: 2022 Tipo de documento: Article