Circular RNA circ_0130438 suppresses TNF-&#945;-induced proliferation, migration, invasion and inflammation in human fibroblast-like MH7A synoviocytes by regulating miR-130a-3p/KLF9 axis.

Li, Lei; Zhan, Minqing; Li, Mingwei

Circular RNA circ_0130438 suppresses TNF-α-induced proliferation, migration, invasion and inflammation in human fibroblast-like MH7A synoviocytes by regulating miR-130a-3p/KLF9 axis.

Li, Lei; Zhan, Minqing; Li, Mingwei.

Afiliação

Li L; Department of Joint Surgery Treatment Center, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi City, Hubei Province, China.
Zhan M; Department of Orthopedics, Weihaiwei People's Hospital, Weihai City, Shandong Province, China.
Li M; Department of Traumatology, Zaozhuang Municipal Hospital Affiliated to Jining Medical College, Zaozhuang City, Shandong Province, China. Electronic address: a18563232890@163.com.

Transpl Immunol ; 72: 101588, 2022 06.

Article em En | MEDLINE | ID: mdl-35358709

Assuntos

Artrite Reumatoide; MicroRNAs; Sinoviócitos; Artrite Reumatoide/genética; Artrite Reumatoide/metabolismo; Artrite Reumatoide/patologia; Proliferação de Células/genética; Células Cultivadas; Citocinas/metabolismo; Fibroblastos; Humanos; Inflamação/metabolismo; Interleucina-6/metabolismo; Interleucina-8/genética; Interleucina-8/metabolismo; Fatores de Transcrição Kruppel-Like/genética; Fatores de Transcrição Kruppel-Like/metabolismo; MicroRNAs/genética; RNA Circular/genética; Sinoviócitos/metabolismo; Sinoviócitos/patologia; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

Circ_0130438; Fibroblast-like synoviocytes (FLSs); KLF9; ceRNA; miR-130a-3p

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / MicroRNAs / Sinoviócitos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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