Chromatin-remodeling factor CHR721 with non-canonical PIP-box interacts with OsPCNA in Rice.
BMC Plant Biol
; 22(1): 164, 2022 Apr 01.
Article
em En
| MEDLINE
| ID: mdl-35365089
ABSTRACT
BACKGROUND:
Proliferating cell nuclear antigen (PCNA) is one of the key factors for the DNA replication process and DNA damage repair. Most proteins interacting with PCNA have a common binding motif PCNA interacting protein box (PIP box). However, some proteins with non-canonical PIP-box have also been reported to be the key factors that interacted with PCNA.RESULTS:
Here we discovered the C terminal of a chromatin-remodeling factor CHR721 with non-canonical PIP-box was essential for interacting with OsPCNA in rice. Both OsPCNA and CHR721 were localized in the nuclei and function in response to DNA damages.CONCLUSIONS:
Based on the results and previous work, we proposed a working model that CHR721 with non-canonical PIP-box interacted with OsPCNA and both of them probably participate in the DNA damage repair process.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Oryza
Tipo de estudo:
Prognostic_studies
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article