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The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL.
Jacobsen, Annette V; Pierotti, Catia L; Lowes, Kym N; Au, Amanda E; Zhang, Ying; Etemadi, Nima; Fitzgibbon, Cheree; Kersten, Wilhelmus J A; Samson, André L; van Delft, Mark F; Huang, David C S; Sabroux, Hélène Jousset; Lessene, Guillaume; Silke, John; Murphy, James M.
Afiliação
  • Jacobsen AV; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Pierotti CL; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
  • Lowes KN; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Au AE; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
  • Zhang Y; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Etemadi N; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
  • Fitzgibbon C; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Kersten WJA; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
  • Samson AL; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • van Delft MF; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
  • Huang DCS; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Sabroux HJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Lessene G; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
  • Silke J; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Murphy JM; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Cell Death Dis ; 13(4): 291, 2022 04 01.
Article em En | MEDLINE | ID: mdl-35365636
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Necroptose Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Necroptose Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article