Dexmedetomidine reduces enteric glial cell injury induced by intestinal ischaemia-reperfusion injury through mitochondrial localization of TERT.

Hu, Qian; Liu, Xiao-Ming; Liu, Zheng-Ren; Liu, Zhi-Yi; Zhang, Huai-Gen; Zhang, Qin; Huang, Yuan-Lu; Chen, Qiu-Hong; Wang, Wen-Xiang; Zhang, XueKang

Hu, Qian; Liu, Xiao-Ming; Liu, Zheng-Ren; Liu, Zhi-Yi; Zhang, Huai-Gen; Zhang, Qin; Huang, Yuan-Lu; Chen, Qiu-Hong; Wang, Wen-Xiang; Zhang, XueKang.

Afiliação

Hu Q; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Liu XM; Department of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Liu ZR; Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Liu ZY; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Zhang HG; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Zhang Q; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Huang YL; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Chen QH; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Wang WX; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Zhang X; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.

J Cell Mol Med ; 26(9): 2594-2606, 2022 05.

Article em En | MEDLINE | ID: mdl-35366055

Assuntos

Dexmedetomidina; Traumatismo por Reperfusão; Telomerase; Animais; Ratos; Dexmedetomidina/farmacologia; DNA Mitocondrial/genética; DNA Mitocondrial/metabolismo; Poro de Transição de Permeabilidade Mitocondrial; Neuroglia/metabolismo; Ratos Wistar; Traumatismo por Reperfusão/complicações; Traumatismo por Reperfusão/tratamento farmacológico; Traumatismo por Reperfusão/metabolismo; Telomerase/metabolismo

Palavras-chave

TERT; dexmedetomidine; enteric glial cells; intestinal ischaemia-reperfusion injury; mitochondrial localization; oxidative stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão / Telomerase / Dexmedetomidina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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