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Infusion of haploidentical NKG2D-CAR-TCD45RA- cells in two pediatric patients with advanced relapsed and refractory acute leukemia was safe but achieved no clinical benefits.
Fernández, Adrián; Pérez-Martínez, Antonio; Escudero, Adela; Mirones, Isabel; González, Berta; de Paz, Raquel; Matamala, Nerea; Clares, Laura; Navarro, Alfonso; Galán, Victor; Martínez-Romera, Isabel; Martínez-López, Joaquín; Leivas, Alejandra; Valés-Gómez, Mar; Ferreras, Cristina; Fernández, Lucía.
Afiliação
  • Fernández A; Hematological Malignancies Lab-H12O Clinical Research Unit, Spanish National Cancer Research Center (CNIO), Madrid, Spain.
  • Pérez-Martínez A; Pediatric Hemato-Oncology Department, La Paz University Hospital, Madrid, Spain.
  • Escudero A; Translational Research Group in Pediatric Oncology Hematopoietic Transplantation and Cell Therapy, La Paz University Hospital Institute for Health Research-IdiPAZ, Madrid, Spain.
  • Mirones I; Pediatric Department, Autonomous University of Madrid, Madrid, Spain.
  • González B; Pediatric Molecular Hemato-Oncology Department, Medical and Molecular Genetics Institute (INGEMM), La Paz University Hospital, Madrid, Spain.
  • de Paz R; Advanced Therapy Medicinal Products Production Unit, Pediatric Hemato-Oncology Service and Pharmacy Service, La Paz University Hospital, Madrid, Spain.
  • Matamala N; Pediatric Hemato-Oncology Department, La Paz University Hospital, Madrid, Spain.
  • Clares L; Hematology and Hemotherapy Department, La Paz University Hospital, Madrid, Spain.
  • Navarro A; Pediatric Molecular Hemato-Oncology Department, Medical and Molecular Genetics Institute (INGEMM), La Paz University Hospital, Madrid, Spain.
  • Galán V; Translational Research Group in Pediatric Oncology Hematopoietic Transplantation and Cell Therapy, La Paz University Hospital Institute for Health Research-IdiPAZ, Madrid, Spain.
  • Martínez-Romera I; Translational Research Group in Pediatric Oncology Hematopoietic Transplantation and Cell Therapy, La Paz University Hospital Institute for Health Research-IdiPAZ, Madrid, Spain.
  • Martínez-López J; Pediatric Hemato-Oncology Department, La Paz University Hospital, Madrid, Spain.
  • Leivas A; Pediatric Hemato-Oncology Department, La Paz University Hospital, Madrid, Spain.
  • Valés-Gómez M; Hematological Malignancies Lab-H12O Clinical Research Unit, Spanish National Cancer Research Center (CNIO), Madrid, Spain.
  • Ferreras C; Hematology Department, 12 de Octubre University Hospital, Madrid, Spain.
  • Fernández L; Hematological Malignancies Lab-H12O Clinical Research Unit, Spanish National Cancer Research Center (CNIO), Madrid, Spain.
Leuk Lymphoma ; 63(8): 1970-1974, 2022 08.
Article em En | MEDLINE | ID: mdl-35369829
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Transplante de Células-Tronco Hematopoéticas / Receptores de Antígenos Quiméricos Limite: Child / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Transplante de Células-Tronco Hematopoéticas / Receptores de Antígenos Quiméricos Limite: Child / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article