Buprenorphine treatment retention and comorbidities among patients with opioid use disorder in a primary care setting.
Am J Addict
; 31(3): 256-260, 2022 05.
Article
em En
| MEDLINE
| ID: mdl-35385169
ABSTRACT
BACKGROUND AND OBJECTIVES:
More information is needed about comorbidities among patients receiving buprenorphine maintenance treatment and their relationship with retention.METHODS:
Retrospective electronic health record data over a 5-year period from primary care patients receiving buprenorphine for the treatment of opioid use disorder were examined (N = 899). The present analysis determined the prevalence of comorbidities and examined associations with treatment retention as defined by cumulative duration of buprenorphine prescription.RESULTS:
Tobacco use and comorbidities including hypertension were prevalent but did not predict retention according to survival analyses controlling for demographic characteristics. Retention was poorer among patients testing positive for cocaine (HR = 1.38, 95% CI 1.09-1.74, p = .007) and patients with hepatitis C virus (HR = 1.17, 95% CI 1.01-1.37, p = .04). CONCLUSION AND SCIENTIFICSIGNIFICANCE:
This study provides new knowledge of previously unexamined associations between comorbidities (e.g., hypertension) and buprenorphine treatment retention. The robust association between cocaine use and poorer buprenorphine retention serves to resolve prior conflicting data in the literature.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Buprenorfina
/
Cocaína
/
Hipertensão
/
Transtornos Relacionados ao Uso de Opioides
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article