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Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery.
Zhou, Tian; Zhu, Xinyi; Ye, Zhizhong; Wang, Yong-Fei; Yao, Chao; Xu, Ning; Zhou, Mi; Ma, Jianyang; Qin, Yuting; Shen, Yiwei; Tang, Yuanjia; Yin, Zhihua; Xu, Hong; Zhang, Yutong; Zang, Xiaoli; Ding, Huihua; Yang, Wanling; Guo, Ya; Harley, John B; Namjou, Bahram; Kaufman, Kenneth M; Kottyan, Leah C; Weirauch, Matthew T; Hou, Guojun; Shen, Nan.
Afiliação
  • Zhou T; Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200001, China.
  • Zhu X; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200032, China.
  • Ye Z; Shenzhen Futian Hospital for Rheumatic Diseases, Shenzhen, 518040, China.
  • Wang YF; Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200001, China.
  • Yao C; Shenzhen Futian Hospital for Rheumatic Diseases, Shenzhen, 518040, China.
  • Xu N; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, 999077, China.
  • Zhou M; Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences (SIBS), University of Chinese Academy of Sciences, Chinese Academy of Sciences (CAS), Shanghai, 200031, China.
  • Ma J; Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200001, China.
  • Qin Y; Sheng Yushou Center of Cell Biology and Immunology, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University (SJTU), Shanghai, 200240, China.
  • Shen Y; Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200001, China.
  • Tang Y; Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200001, China.
  • Yin Z; Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200001, China.
  • Xu H; Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200001, China.
  • Zhang Y; Shenzhen Futian Hospital for Rheumatic Diseases, Shenzhen, 518040, China.
  • Zang X; Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200127, China.
  • Ding H; Shanghai Key Laboratory of Gynecologic Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200127, China.
  • Yang W; Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200001, China.
  • Guo Y; Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200001, China.
  • Harley JB; Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, 200001, China.
  • Namjou B; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, 999077, China.
  • Kaufman KM; Sheng Yushou Center of Cell Biology and Immunology, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University (SJTU), Shanghai, 200240, China.
  • Kottyan LC; US Department of Veterans Affairs Medical Center, Cincinnati, OH, 45229, USA.
  • Weirauch MT; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.
  • Hou G; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.
  • Shen N; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.
Nat Commun ; 13(1): 1855, 2022 04 06.
Article em En | MEDLINE | ID: mdl-35388006
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / RNA Longo não Codificante Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / RNA Longo não Codificante Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article