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CRISPR-Cas9 Targeting of Hepatitis B Virus Covalently Closed Circular DNA Generates Transcriptionally Active Episomal Variants.
Martinez, Maria Guadalupe; Combe, Emmanuel; Inchauspe, Aurore; Mangeot, Philippe Emmanuel; Delberghe, Elodie; Chapus, Fleur; Neveu, Gregory; Alam, Antoine; Carter, Kara; Testoni, Barbara; Zoulim, Fabien.
Afiliação
  • Martinez MG; INSERM U1052, CNRS UMR-5286, Cancer Research Center of Lyon, Lyon, France.
  • Combe E; INSERM U1052, CNRS UMR-5286, Cancer Research Center of Lyon, Lyon, France.
  • Inchauspe A; INSERM U1052, CNRS UMR-5286, Cancer Research Center of Lyon, Lyon, France.
  • Mangeot PE; Evotec, Lyon, France.
  • Delberghe E; Centre International de Recherche en Infectiologie, INSERM U1111, CNRS UMR-5308, INSERM and Ecole Normale Superieure de Lyon, Lyon, France.
  • Chapus F; INSERM U1052, CNRS UMR-5286, Cancer Research Center of Lyon, Lyon, France.
  • Neveu G; INSERM U1052, CNRS UMR-5286, Cancer Research Center of Lyon, Lyon, France.
  • Alam A; Evotec, Lyon, France.
  • Carter K; Evotec, Lyon, France.
  • Testoni B; Evotec, Lyon, France.
  • Zoulim F; INSERM U1052, CNRS UMR-5286, Cancer Research Center of Lyon, Lyon, France.
mBio ; 13(2): e0288821, 2022 04 26.
Article em En | MEDLINE | ID: mdl-35389262
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus da Hepatite B / Hepatite B Crônica Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus da Hepatite B / Hepatite B Crônica Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article