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Novel 3-(6-methylpyridin-2-yl)coumarin-based chalcones as selective inhibitors of cancer-related carbonic anhydrases IX and XII endowed with anti-proliferative activity.
Tawfik, Haytham O; Shaldam, Moataz A; Nocentini, Alessio; Salem, Rofaida; Almahli, Hadia; Al-Rashood, Sara T; Supuran, Claudiu T; Eldehna, Wagdy M.
Afiliação
  • Tawfik HO; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt.
  • Shaldam MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
  • Nocentini A; Section of Pharmaceutical and Nutraceutical Sciences, Department of NEUROFARBA, University of Florence, Polo Scientifico, Firenze, Italy.
  • Salem R; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
  • Almahli H; Department of Chemistry, University of Cambridge, Cambridge, UK.
  • Al-Rashood ST; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
  • Supuran CT; Section of Pharmaceutical and Nutraceutical Sciences, Department of NEUROFARBA, University of Florence, Polo Scientifico, Firenze, Italy.
  • Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
J Enzyme Inhib Med Chem ; 37(1): 1043-1052, 2022 Dec.
Article em En | MEDLINE | ID: mdl-35437108
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Chalcona / Anidrases Carbônicas / Chalconas / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Chalcona / Anidrases Carbônicas / Chalconas / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article