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Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-ß-mediated Smad2/3 phosphorylation.
Chen, Shunlun; Lei, Linchuan; Li, Zemin; Chen, Fan; Huang, Yuming; Jiang, Guowei; Guo, Xingyu; Zhao, Zhuoyang; Liu, Hui; Wang, Hua; Liu, Caijun; Zheng, Zhaomin; Wang, Jianru.
Afiliação
  • Chen S; Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, 510080, Guangzhou, China.
  • Lei L; Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, 510080, Guangzhou, China.
  • Li Z; Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, 510080, Guangzhou, China.
  • Chen F; Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, 510080, Guangzhou, China.
  • Huang Y; Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, 510080, Guangzhou, China.
  • Jiang G; Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, 510080, Guangzhou, China.
  • Guo X; Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, 510080, Guangzhou, China.
  • Zhao Z; Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, 510080, Guangzhou, China.
  • Liu H; Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, 510080, Guangzhou, China.
  • Wang H; Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, 510080, Guangzhou, China.
  • Liu C; Department of Spine Surgery, The Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, 510378, Guangzhou, China.
  • Zheng Z; Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, 510080, Guangzhou, China. zhzhaom@mail.sysu.edu.cn.
  • Wang J; Pain Research Center, Sun Yat-Sen University, 510080, Guangzhou, China. zhzhaom@mail.sysu.edu.cn.
Exp Mol Med ; 54(4): 518-530, 2022 04.
Article em En | MEDLINE | ID: mdl-35440754
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citocinas / Degeneração do Disco Intervertebral / Núcleo Pulposo Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citocinas / Degeneração do Disco Intervertebral / Núcleo Pulposo Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article