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Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma.
Guidi, Riccardo; Xu, Daqi; Choy, David F; Ramalingam, Thirumalai R; Lee, Wyne P; Modrusan, Zora; Liang, Yuxin; Marsters, Scot; Ashkenazi, Avi; Huynh, Alison; Mills, Jessica; Flanagan, Sean; Hambro, Shannon; Nunez, Victor; Leong, Laurie; Cook, Ashley; Tran, Tiffany Hao; Austin, Cary D; Cao, Yi; Clarke, Christine; Panettieri, Reynold A; Koziol-White, Cynthia; Jester, William F; Wang, Fen; Wilson, Mark S.
Afiliação
  • Guidi R; Immunology Discovery, Genentech, South San Francisco, CA 94080, USA.
  • Xu D; Immunology Discovery, Genentech, South San Francisco, CA 94080, USA.
  • Choy DF; Biomarker Discovery OMNI, Genentech, South San Francisco, CA 94080, USA.
  • Ramalingam TR; Biomarker Discovery OMNI, Genentech, South San Francisco, CA 94080, USA.
  • Lee WP; Translational Immunology, Genentech, South San Francisco, CA 94080, USA.
  • Modrusan Z; Next Generation Sequencing (NGS), Genentech, South San Francisco, CA 94080, USA.
  • Liang Y; Next Generation Sequencing (NGS), Genentech, South San Francisco, CA 94080, USA.
  • Marsters S; Cancer Immunology, Genentech, South San Francisco, CA 94080, USA.
  • Ashkenazi A; Cancer Immunology, Genentech, South San Francisco, CA 94080, USA.
  • Huynh A; Necropsy, Genentech, South San Francisco, CA 94080, USA.
  • Mills J; Necropsy, Genentech, South San Francisco, CA 94080, USA.
  • Flanagan S; Necropsy, Genentech, South San Francisco, CA 94080, USA.
  • Hambro S; Necropsy, Genentech, South San Francisco, CA 94080, USA.
  • Nunez V; Necropsy, Genentech, South San Francisco, CA 94080, USA.
  • Leong L; Pathology, Genentech, South San Francisco, CA 94080, USA.
  • Cook A; Pathology, Genentech, South San Francisco, CA 94080, USA.
  • Tran TH; Pathology, Genentech, South San Francisco, CA 94080, USA.
  • Austin CD; Pathology, Genentech, South San Francisco, CA 94080, USA.
  • Cao Y; OMNI Bioinformatics, Genentech, South San Francisco, CA 94080, USA.
  • Clarke C; OMNI Bioinformatics, Genentech, South San Francisco, CA 94080, USA.
  • Panettieri RA; Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ 08901, USA.
  • Koziol-White C; Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ 08901, USA.
  • Jester WF; Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ 08901, USA.
  • Wang F; Center for Cancer Biology and Nutrition, Texas A&M University, Houston, TX 77030, USA.
  • Wilson MS; Immunology Discovery, Genentech, South San Francisco, CA 94080, USA.
Sci Transl Med ; 14(641): eabl8146, 2022 04 20.
Article em En | MEDLINE | ID: mdl-35442706
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Fatores de Crescimento de Fibroblastos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Fatores de Crescimento de Fibroblastos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article