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Engineered Cas12a-Plus nuclease enables gene editing with enhanced activity and specificity.
Huang, Hongxin; Huang, Guanjie; Tan, Zhihong; Hu, Yongfei; Shan, Lin; Zhou, Jiajian; Zhang, Xin; Ma, Shufeng; Lv, Weiqi; Huang, Tao; Liu, Yuchen; Wang, Dong; Zhao, Xiaoyang; Lin, Ying; Rong, Zhili.
Afiliação
  • Huang H; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
  • Huang G; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Tan Z; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Hu Y; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
  • Shan L; Department of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Zhou J; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Zhang X; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
  • Ma S; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Lv W; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Huang T; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
  • Liu Y; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
  • Wang D; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Zhao X; Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, 510515, China.
  • Lin Y; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
  • Rong Z; Department of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
BMC Biol ; 20(1): 91, 2022 04 25.
Article em En | MEDLINE | ID: mdl-35468792
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Edição de Genes Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Edição de Genes Idioma: En Ano de publicação: 2022 Tipo de documento: Article