Assessment of the virulence for chickens of Newcastle Disease virus with an engineered multi-basic cleavage site in the fusion protein and disrupted V protein gene.

de Graaf, J F; van Nieuwkoop, S; de Meulder, D; Lexmond, P; Kuiken, T; Groeneveld, D; Fouchier, R A M; van den Hoogen, B G

de Graaf, J F; van Nieuwkoop, S; de Meulder, D; Lexmond, P; Kuiken, T; Groeneveld, D; Fouchier, R A M; van den Hoogen, B G.

Afiliação

de Graaf JF; Viroscience Department, Erasmus Medical Centrum, Rotterdam, the Netherlands.
van Nieuwkoop S; Viroscience Department, Erasmus Medical Centrum, Rotterdam, the Netherlands.
de Meulder D; Viroscience Department, Erasmus Medical Centrum, Rotterdam, the Netherlands.
Lexmond P; Viroscience Department, Erasmus Medical Centrum, Rotterdam, the Netherlands.
Kuiken T; Viroscience Department, Erasmus Medical Centrum, Rotterdam, the Netherlands.
Groeneveld D; Viroscience Department, Erasmus Medical Centrum, Rotterdam, the Netherlands.
Fouchier RAM; Viroscience Department, Erasmus Medical Centrum, Rotterdam, the Netherlands.
van den Hoogen BG; Viroscience Department, Erasmus Medical Centrum, Rotterdam, the Netherlands. Electronic address: b.vandenhoogen@erasmusmc.nl.

Vet Microbiol ; 269: 109437, 2022 Jun.

Article em En | MEDLINE | ID: mdl-35472508

Assuntos

Doença de Newcastle; Doenças das Aves Domésticas; Animais; Galinhas; Vírus da Doença de Newcastle/genética; Proteínas Virais de Fusão/genética; Proteínas Virais de Fusão/metabolismo; Virulência/genética

Palavras-chave

Chickens; Multi-basic cleavage site; Newcastle Disease virus; Pathogenesis; Viro-immunotherapy; Virulence

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças das Aves Domésticas / Doença de Newcastle Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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