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Small-molecule IKKß activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth.
Napoleon, John Victor; Sagar, Satish; Kubica, Sydney P; Boghean, Lidia; Kour, Smit; King, Hannah M; Sonawane, Yogesh A; Crawford, Ayrianne J; Gautam, Nagsen; Kizhake, Smitha; Bialk, Pawel A; Kmiec, Eric; Mallareddy, Jayapal Reddy; Patil, Prathamesh P; Rana, Sandeep; Singh, Sarbjit; Prahlad, Janani; Grandgenett, Paul M; Borgstahl, Gloria E O; Ghosal, Gargi; Alnouti, Yazen; Hollingsworth, Michael A; Radhakrishnan, Prakash; Natarajan, Amarnath.
Afiliação
  • Napoleon JV; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Sagar S; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Kubica SP; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Boghean L; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Kour S; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • King HM; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Sonawane YA; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Crawford AJ; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Gautam N; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198.
  • Kizhake S; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Bialk PA; Gene Editing Institute, Christiana Care, Newark, DE 19713.
  • Kmiec E; Gene Editing Institute, Christiana Care, Newark, DE 19713.
  • Mallareddy JR; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Patil PP; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Rana S; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Singh S; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Prahlad J; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Grandgenett PM; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Borgstahl GEO; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Ghosal G; Department of Genetics Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE 68198.
  • Alnouti Y; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198.
  • Hollingsworth MA; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
  • Radhakrishnan P; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198.
  • Natarajan A; Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198.
Proc Natl Acad Sci U S A ; 119(18): e2115071119, 2022 05 03.
Article em En | MEDLINE | ID: mdl-35476515
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / MAP Quinase Quinase Quinase 1 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / MAP Quinase Quinase Quinase 1 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article