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Foldamers reveal and validate therapeutic targets associated with toxic α-synuclein self-assembly.
Ahmed, Jemil; Fitch, Tessa C; Donnelly, Courtney M; Joseph, Johnson A; Ball, Tyler D; Bassil, Mikaela M; Son, Ahyun; Zhang, Chen; Ledreux, Aurélie; Horowitz, Scott; Qin, Yan; Paredes, Daniel; Kumar, Sunil.
Afiliação
  • Ahmed J; Molecular and Cellular Biophysics Program, University of Denver, Denver, CO, 80210, USA.
  • Fitch TC; The Knoebel Institute for Healthy Aging, University of Denver, Denver, CO, 80210, USA.
  • Donnelly CM; The Knoebel Institute for Healthy Aging, University of Denver, Denver, CO, 80210, USA.
  • Joseph JA; Department of Chemistry and Biochemistry, University of Denver, Denver, CO, 80210, USA.
  • Ball TD; The Knoebel Institute for Healthy Aging, University of Denver, Denver, CO, 80210, USA.
  • Bassil MM; Department of Chemistry and Biochemistry, University of Denver, Denver, CO, 80210, USA.
  • Son A; The Knoebel Institute for Healthy Aging, University of Denver, Denver, CO, 80210, USA.
  • Zhang C; Department of Chemistry and Biochemistry, University of Denver, Denver, CO, 80210, USA.
  • Ledreux A; The Knoebel Institute for Healthy Aging, University of Denver, Denver, CO, 80210, USA.
  • Horowitz S; Department of Chemistry and Biochemistry, University of Denver, Denver, CO, 80210, USA.
  • Qin Y; The Knoebel Institute for Healthy Aging, University of Denver, Denver, CO, 80210, USA.
  • Paredes D; Department of Chemistry and Biochemistry, University of Denver, Denver, CO, 80210, USA.
  • Kumar S; The Knoebel Institute for Healthy Aging, University of Denver, Denver, CO, 80210, USA.
Nat Commun ; 13(1): 2273, 2022 04 27.
Article em En | MEDLINE | ID: mdl-35477706

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Alfa-Sinucleína Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Alfa-Sinucleína Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article