The prognostic miR-532-5p-correlated ceRNA-mediated lipid droplet accumulation drives nodal metastasis of cervical cancer.
J Adv Res
; 37: 169-184, 2022 03.
Article
em En
| MEDLINE
| ID: mdl-35499057
Palavras-chave
ACC1, Acetyl-CoA carboxylase 1; ACOX1, Acyl-CoA oxidase 1; ATCC, The American Type Culture Collection; BMI, Body mass index; CC, Cervical cancer; CPAT, The coding potential assessment tool; CPT1A, Carnitine palmitoyltransferase-1A; Cervical cancer; CircRNAs, circular RNAs; DFS, Disease free survival; EMT, Epithelial-mesenchymal transition; ES, enrichment score; FA, Fatty acid; FASN; FASN, Fatty acid synthase; GEPIA, The Gene Expression Profiling Interactive Analysis; GSEA, Gene set enrichment analysis; HE, Hematoxylin-eosin; HLECs, Human lymphatic endothelial cells; IHC, immunohistochemistry; ISH, In situ hybridization; LASSO, The least absolute shrinkage and selection operator; LDs, Lipid droplets; LINC01410, Long non-coding RNA 01410; LNM, lymph node metastasis; Lipid droplet; LncRNAs, Long noncoding RNAs; Lymph node metastasis; MES, Maximum enrichment score; MREs, MiRNA response elements; Mfe, The minimum free energy; NCF2, Neutrophil cytosolic factor 2; OS, Overall survival; PLIN2, Perilipin 2; PLs, Phospholipids; RIP, RNA immunoprecipitation; ROC, The receiver operating characteristic; SNR, signal-to-noise ratio; STR, short tandem repeat; TCGA, The Cancer Genome Atlas; TGs, Triglycerides; ceRNA, Competing endogenous RNA; miRNA prognostic model; miRNAs, MicroRNAs; ncRNAs, Noncoding RNAs
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias do Colo do Útero
/
MicroRNAs
Tipo de estudo:
Prognostic_studies
Limite:
Female
/
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article