Synthesis of novel combinatorial drug delivery system (nCDDS) for co-delivery of 5-fluorouracil and leucovorin calcium for colon targeting and controlled drug release.

Minhas, Muhammad Usman; Abdullah, Orva; Sohail, Muhammad; Khalid, Ikrima; Ahmad, Sarfaraz; Khan, Kifayat Ullah; Badshah, Syed Faisal

Minhas, Muhammad Usman; Abdullah, Orva; Sohail, Muhammad; Khalid, Ikrima; Ahmad, Sarfaraz; Khan, Kifayat Ullah; Badshah, Syed Faisal.

Afiliação

Minhas MU; College of Pharmacy, University of Sargodha, Sargodha, Pakistan.
Abdullah O; Hamdard Institute of Pharmaceutical Sciences, Hamdard University, Islamabad, Pakistan.
Sohail M; Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Khalid I; Department of Pharmacy, COMSATS University, Abbottabad, Pakistan.
Ahmad S; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, GC University Faisalabad, Faisalabad, Pakistan.
Khan KU; Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Badshah SF; Quaid-e-Azam College of Pharmacy, Sahiwal, Pakistan.

Drug Dev Ind Pharm ; 47(12): 1952-1965, 2021 Dec.

Article em En | MEDLINE | ID: mdl-35502653

Assuntos

Cálcio; Fluoruracila; Animais; Colo; Portadores de Fármacos/química; Sistemas de Liberação de Medicamentos/métodos; Liberação Controlada de Fármacos; Fluoruracila/química; Géis/química; Leucovorina; Nanogéis; Coelhos

Palavras-chave

5-fluorouracil; Combinatorial gel; colon targeting; controlled release; leucovorin calcium

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cálcio / Fluoruracila Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cálcio / Fluoruracila Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article