The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside.

Sun, Xin; Hong, Yeting; Shu, Yuhan; Wu, Caixia; Ye, Guiqin; Chen, Hanxiao; Zhou, Hongying; Gao, Ruilan; Zhang, Jianbin.

Afiliação

Sun X; Department of Oncology, Cancer Center of Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Hong Y; Hangzhou Medical College, Hangzhou, China.
Shu Y; College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China.
Wu C; Clinical Research Institute, Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Ye G; Hangzhou Medical College, Hangzhou, China.
Chen H; Wenzhou Medical University, Wenzhou, China.
Zhou H; Department of Oncology, Cancer Center of Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Gao R; Institution of Hematology Research, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Zhang J; Clinical Research Institute, Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, People's Hospital of Hangzhou Medical College, Hangzhou, China.

J Ginseng Res ; 46(2): 266-274, 2022 Mar.

Article em En | MEDLINE | ID: mdl-35509820

Palavras-chave

BNIP3, BCL2 interacting protein 3; COX â£, cytochrome c oxidase â£; GAPDH; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GSH, glutathione; Gensinoside; HSP60, heat shock protein 60 KDa; LC3, microtubule-associated proteins 1A/1B light chain 3; MFN2, mitofusion 2; Mitophagy; PARK2, Parkin; PHGDH, phosphoglycerate dehydrogenase; PINK1, PTEN induced putative kinase 1; Parkin; ROS; SQSTM1, sequestosome 1; TIM23, translocase of the inner membrane 23; TOMM20, translocase of outer mitochondrial membrane 20; Ubiquitination; VDAC1, voltage-dependent anion-selective channel protein 1

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article