JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage.

Liu, Changjiang; Wu, Mingzhu; Qu, Jiayuan; Huang, Xu; Zeng, Qiang; Ha, Mei

Liu, Changjiang; Wu, Mingzhu; Qu, Jiayuan; Huang, Xu; Zeng, Qiang; Ha, Mei.

Afiliação

Liu C; NHC Key Laboratory of Birth Defects and Reproductive Health, Chongqing Population and Family Planning Science and Technology Research Institute, Chongqing 400020, PR China; Medical Research Institute, Southwest University, Chongqing 400715, PR China.
Wu M; Medical Research Institute, Southwest University, Chongqing 400715, PR China.
Qu J; NHC Key Laboratory of Birth Defects and Reproductive Health, Chongqing Population and Family Planning Science and Technology Research Institute, Chongqing 400020, PR China.
Huang X; NHC Key Laboratory of Birth Defects and Reproductive Health, Chongqing Population and Family Planning Science and Technology Research Institute, Chongqing 400020, PR China.
Zeng Q; Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (incubating), School of Public Health, Tongji Medical College, Huazhong University of Scie
Ha M; Chongqing Medical and Pharmaceutical College, Chongqing 400030, PR China. Electronic address: cj_514@163.com.

Ecotoxicol Environ Saf ; 238: 113582, 2022 Jun 15.

Article em En | MEDLINE | ID: mdl-35512476

Assuntos

Quimiocina CXCL16; Proteína Jagged-1; Rim; MAP Quinase Quinase 4; MicroRNAs; Piretrinas; Animais; Quimiocina CXCL16/genética; Quimiocina CXCL16/metabolismo; Inflamação/genética; Inflamação/metabolismo; Proteína Jagged-1/genética; Proteína Jagged-1/metabolismo; Rim/efeitos dos fármacos; Rim/metabolismo; MAP Quinase Quinase 4/metabolismo; MicroRNAs/metabolismo; Piretrinas/toxicidade; Ratos; Ratos Sprague-Dawley; Receptor Notch2/genética; Receptor Notch2/metabolismo

Palavras-chave

CXCL16; Cypermethrin; JNK/c-Jun pathway; Jag1/Notch2/Hes1 pathway; Kidney damage

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piretrinas / MicroRNAs / MAP Quinase Quinase 4 / Proteína Jagged-1 / Quimiocina CXCL16 / Rim Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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