[The Genetic Basis of ADHD - An Update]. / Genetische Grundlagen der ADHS ein Update.
Z Kinder Jugendpsychiatr Psychother
; 50(3): 203-217, 2021 May.
Article
em De
| MEDLINE
| ID: mdl-35514173
ABSTRACT
The Genetic Basis of ADHD - An Update Abstract. Genetic risks play an important role in the etiology of attention-deficit/hyperactivity disorder (ADHD). This review presents the current state of knowledge concerning the genetic basis of the disorder. It discusses the results of twin- and family-based studies, linkage and association studies as well as recent findings resulting from Genome Wide Association Studies (GWAS). Furthermore, it elaborates on the relevance of polygenic risk scores, rare variants, and epigenetic alterations, especially in light of findings on genetic pleiotropy in the context of frequent psychiatric comorbidities in patients with ADHD.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transtorno do Deficit de Atenção com Hiperatividade
/
Estudo de Associação Genômica Ampla
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
De
Ano de publicação:
2021
Tipo de documento:
Article